Science of Conflict How do nerve agents work? |
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Nerves communicate with different parts of the body through chemical substances known as neurotransmitters. Click to find out more about nerves. |
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Muscles are stimulated by nerves via a neurotransmitter called acetylcholine. This chemical is released into the synapse and binds with receptors on the surface of the muscle where it causes a muscular contraction to take place. Soon after the acetylcholine is destroyed by a chemical called acetylcholinesterase. The muscle is no longer stimulated and relaxes. | |
Nerve agents stop the ability of acetylcholinesterase to destroy acetylcholine and cause the muscle to relax. As a result acetylcholine lingers on the receptor and continues to excite the muscle, as shown on the right. This causes a lack of muscular control and eventually the organism dies of suffocation. | |